'The 49ers set themselves apart by dominating the last three quarters of that game. 'Obviously, with that impressive performance, the 49ers are the clear Super Bowl favorite at +300,' Caesars Sports assistant director of trading Adam Pullen said. The 49ers went to Philadelphia as 3-point favorites and administered a 42-19 beatdown of the defending NFC champion Eagles (10-2 SU). San Fran (9-3 SU) is on a four-game win streak and made a huge statement in its most recent victory. Now, though, the dominant Niners are back.
But they were also a bit banged up and quickly fell back to earth, losing three in a row. San Francisco stormed through its first five games, capped by a 42-10 demolition of Dallas. Christian McCaffrey and the 49ers are consensus favorites in Super Bowl odds.